Binding chicken Anx2 is beneficial for infection with infectious bursal disease virus
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- 作者：Xiangang Rena ; 1 ; renxiangang@caas.cn" class="auth_mail" title="E-mail the corresponding author ; Lizhou Zhanga ; 1 ; zhanglizhou88@126.com" class="auth_mail" title="E-mail the corresponding author ; Yulong Gaoa ; ylg@hvri.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Honglei Gaoa ; ghl@hvri.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Yongqiang Wanga ; yqw@hvri.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Changjun Liua ; liucj93711@hvri.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Hongyu Cuia ; cuihongyu@caas.cn" class="auth_mail" title="E-mail the corresponding author ; Yanping Zhanga ; zhyp_77@hvri.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Lili Jianga ; lyjllfxy1024@163.com" class="auth_mail" title="E-mail the corresponding author ; Xiaole Qia ; qxl@hvri.ac.cn" class="auth_mail" title="E-mail the corresponding author ; Xiaomei Wanga ; b ; xmw@hvri.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Chicken Anx2 ; IBDV ; Binding ; Virus infection
- 刊名：Virus Research
- 出版年：2015
- 出版时间：2 December 2015
- 年：2015
- 卷：210
- 期：Complete
- 页码：232-240
- 全文大小：1787 K
文摘
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The identification of host cellular molecules that binds with virus will improve the understanding of the pathogenic mechanism. However, the identification of a specific protein of host cell for the binding of IBDV has been elusive. In this study, a new molecular, chicken Anx2 was identified that can bind with IBDV.
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Previous reporters showed that Anx2 implicated in the infection of certain viruses. However, the role of Anx2 in the IBDV infection is unknown. In this study, we first identified chicken Anx2 as binding protein of IBDV and showed that binding with Anx2 is beneficial for IBDV infection.