A joint experimental-computational investigation: Metal organic framework as a vortex assisted dispersive micro-solid-phase extraction sorbent coupled with UPLC-MS/MS for the simultaneous determination of amphenicols and their metabolite in aquaculture water
MIL-101(Cr) for vortex assisted dispersive micro-solid-phase extraction was investigated. MIL-101(Cr) was firstly applied in the analysis of amphenicols and the metabolite at trace level in aquaculture samples. Computer-aided molecular simulation was applied to demonstrate the interaction mechanism of MIL-101(Cr) towards analytes.