Fluorescence turn-on sensing of ascorbic acid and alkaline phosphatase activity based on graphene quantum dots
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- 作者：Hui Huanga ; c ; huanghui@jlu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; huanghui3048@163.com" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae ; Bingdi Wanga ; cAuthor Vitae ; Meng ChenaAuthor Vitae ; Mengxian LiuaAuthor Vitae ; Yue LengaAuthor Vitae ; Xinyang LiuaAuthor Vitae ; Yongxin Lib ; liyongxin@ciac.ac.cn" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae ; Zhenning LiucAuthor Vitae
- 关键词：Graphene quantum dots ; Turn-on sensor ; Ascorbic acid ; Alkaline phosphatase
- 刊名：Sensors & Actuators: B. Chemical
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：235
- 期：Complete
- 页码：356-361
- 全文大小：1474 K
文摘
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A simple ALP detection method was developed based on graphene quantum dots.
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The method has fairly good sensitivity and selectivity.
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Turn-off approach was used for sensing para-benzoquinone and turn-on for sensing l-ascorbic acid.
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A fluorescent turn-on strategy considerably reduces the possible false positive signals.
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The method could be used for the screening of potential ALP inhibitors.