Inward rectifier K+ channel and T-type Ca2 + channel contribute to enhancement of GABAergic transmission induced by β1-adrenoceptor in the prefrontal cortex
Dobutamine enhances GABAergic transmission onto pyramidal neurons. T-type Ca2 + channel is involved in dobutamine-enhanced GABA release. Dobutamine depolarizates GABAergic interneurons through inhibition of Kir.