LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P via the PI3K/AKT pathway
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- 作者：ZhiZhen Lia ; b ; 1 ; YuanYuan Chena ; b ; 1 ; XuAn Wanga ; b ; 1 ; HongChen Zhanga ; b ; Yijian Zhanga ; b ; YaoHui Gaoa ; b ; Mingzhe Wenga ; b ; Lei Wanga ; b ; HaiBin Lianga ; b ; MaoLan Lia ; b ; Fei Zhanga ; b ; Shuai Zhaoa ; b ; Shibo Liua ; b ; Yang Caoa ; b ; Yijun Shua ; b ; Runfa Baoa ; b ; Jian Zhoua ; b ; Xiyong Liua ; b ; Yun Yana ; b ; Lei Zhena ; b ; Qian Donga ; b ; dongqian71@163.com" class="auth_mail" title="E-mail the corresponding author ; Yingbin Liua ; b ; liuybphd@126.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Gallbladder cancer ; LASP-1 ; S100P ; Proliferation ; Metastasis ; Cell cycle
- 刊名：Cancer Letters
- 出版年：2016
- 出版时间：28 March 2016
- 年：2016
- 卷：372
- 期：2
- 页码：239-250
- 全文大小：7007 K
文摘
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This study investigated the effects of LASP1 and S100P on the growth of GBC cells.
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LASP-1 effects biological functions of GBC cells by down-regulating S100P via the PI3K/AKT pathway.