Expression and secretion pattern of FljB of Salmonella enterica serovar Typhi in different culture conditions
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- 作者：Xueming Zheng ; Qisi Zhang ; Ying Ji ; Xin Zhao ; Bin Ni ; Shungao Xu ; Xinxiang Huang ; huxinx@ujs.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Salmonella enterica serovar Typhi ; FljB ; SPI-1 inducing condition ; SPI-2 inducing condition ; Secretion
- 刊名：Microbial Pathogenesis
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：95
- 期：Complete
- 页码：142-147
- 全文大小：903 K
文摘
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Flagellin of Salmonella is highly immunogenic and is a key protein recognized by the host immune system.
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SPI-1 inducing condition increases the secretion but not the expression level of FljB.
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SPI-2 inducing condition shut down the expression and consequential secretion of FljB.
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Salmonella may subvert the host's innate immune system through regulation of the expression and secretion of Flagellin.