Promotion of enamel caries remineralization by an amelogenin-derived peptide in a rat model

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• 作者：Sili Han^a ; Yingying Fan^a ; Zhengli Zhou^b ; Huanxin Tu^a ; Danxue Li^a ; Xueping Lv^a ; Longjiang Ding^a ; Linglin Zhang^a ; ^{zhanglinglin_sc@163.com}
• 关键词：Amelogenin ; Peptide ; Caries ; Remineralization ; Rat ; In vivo model
• 刊名：Archives of Oral Biology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：73
• 期：Complete
• 页码：66-71
• 全文大小：1264 K
• 卷排序：73

文摘

A novel peptide based on amelogenin had been confirmed to promote remineralization in an in vitro pH-cycling model. A classic animal caries model was adopted to explore whether this peptide has same effects in vivo. This amelogenin-based peptide can promote remineralization in rat caries model. This peptide shows strong potential for treating enamel caries in clinic.