Simultaneous determination of dopamine and uric acid using layer-by-layer graphene and chitosan assembled multilayer films

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• 作者：Xuexiang Weng ; Qingxue Cao ; Lixin Liang ; Jianrong Chen ; Chunping You ; Yongmin Ruan ; Hongjun Lin ; Lanju Wu
• 关键词：Layer-by-layer ; Graphene ; Chitosan ; Dopamine ; Uric acid
• 刊名：Talanta
• 出版年：15 December, 2013
• 年：2013
• 卷：117
• 期：Complete
• 页码：359-365
• 全文大小：1166 K

文摘

Multilayer films containing graphene (Gr) and chitosan (CS) were prepared on glassy carbon electrodes with layer-by-layer (LBL) assembly technique. After being characterized with cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and scanning electron microscopy (SEM), the electrochemical sensor based on the resulted films was developed to simultaneously determine dopamine (DA) and uric acid (UA). The LBL assembled electrode showed excellent electrocatalytic activity towards the oxidation of DA and UA. In addition, the self-assembly electrode possessed an excellent sensing performance for detection of DA and UA with a linear range from 0.1 渭M to 140 碌M and from 1.0 碌M to 125 碌M with the detection limit as low as 0.05 碌M and 0.1 碌M based on S/N=3, respectively.