The association of gasping and outcome, in out of hospital cardiac arrest: A systematic review and meta-analysis

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• 作者：Lianxing Zhao ; Chunsheng Li ; ^{lcscyyy@163.com" class="auth_mail" title="E-mail the corresponding author} ; Bo Liu ; Miaomiao Wang ; Rui Shao ; Yingying Fang
• 关键词：Respiration ; Out-of-hospital cardiac arrest ; Resuscitation ; Patient admission ; Patient discharge ; Meta-analysis
• 刊名：Resuscitation
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：97
• 期：Complete
• 页码：7-12
• 全文大小：995 K

文摘

Gasping is common after cardiac arrest, and its frequency decreases over time. The aim of this study was to conduct a meta-analysis to evaluate the association of gasping and survival to discharge in patients who suffered out-of-hospital cardiac arrest.

Methods

Relevant studies were identified by searching in PubMed, Medline, Embase, OVID, Web of Science and Google Scholar. Risk ratios (RR) and 95% confidence intervals (CI) were calculated to assess the association of gasping and on out-of-hospital cardiac arrest outcomes. Heterogeneity, subgroup analysis, sensitivity analysis and publication bias were explored.

Results

Individual patient data was obtained from 10,797 participants suffered out-of-hospital cardiac arrest in five cohort studies of 4 articles. A fixed effects model suggested that patients with gasping were 3.525 times (95% CI: 3.028–4.104; P < 0.01) more likely to survive to discharge than those without gasping, and there was no heterogeneity among studies (P = 0.564). Also it may be a favorable factor for return of spontaneous circulation (RR: 2.170; 95% CI: 1.691, 2.785) with high heterogeneity (Q = 5.26; P = 0.022).

Conclusions

Findings of this meta-analysis demonstrated that gasping is common after cardiac arrest, and is associated with increased survival to discharge. Patients who are cardiac arrest with gasping should be promptly resuscitated.