Molecular characterization and expression analyses of three RIG-I-like receptor signaling pathway genes (MDA5, LGP2 and MAVS) in Larimichthys crocea
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- 作者：Bin Shen ; Yiwen Hu ; Shuyi Zhang ; Jialang Zheng ; Lin Zeng ; Jianshe Zhang ; Aiyi Zhu ; Changwen Wu ; shenbinzjou@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Large yellow croaker ; Innate antiviral immunity ; Pattern recognition receptor ; Poly (I ; C) ; RT-qPCR
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：55
- 期：Complete
- 页码：535-549
- 全文大小：4263 K
文摘
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LcMDA5, LcLGP2 and LcMAVS were sequenced from Larimichthys crocea.
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LcMDA5, LcLGP2 and LcMAVS all express ubiquitously but with relatively low levels.
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LcMDA5, LcLGP2 and LcMAVS were significantly upregulated after poly(I:C) challenge.
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LcMDA5, LcLGP2 and LcMAVS play important roles in antiviral immune responses.