Spectroscopic studies on the interactions between novel bisnaphthalimide derivatives and calf thymus DNA

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• 作者：Dongye He¹ ; Lili Wang¹ ; Liping Wang ; Xiaoyu Li ; Yongping Xu ; ^{hechen2287@sina.com}
• 关键词：Bisnaphthalimide ; Calf thymus DNA ; Spectroscopy ; Binding mode
• 刊名：Journal of Photochemistry and Photobiology B: Biology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：166
• 期：Complete
• 页码：333-340
• 全文大小：1314 K
• 卷排序：166

文摘

Various spectroscopic techniques were used to explore the binding mode. Six compounds interacted with DNA by intercalative and electrostatic binding mode. Binding constants and sites were determined. Substituent group with smaller space offered easier intercalative binding. The electrostatic binding ability was independent of the type of linkers.