Efficacy of triple therapy with esomeprazole, amoxicillin, and sitafloxacin as a third-line Helicobacter pylori eradication regimen
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- 作者：Yoshihiro Hirata ; Hiratay-int@h.u-tokyo.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Takako Serizawa ; Satoki Shichijo ; Nobumi Suzuki ; Kosuke Sakitani ; Yoku Hayakawa ; Atsuo Yamada ; Kazuhiko Koike
- 关键词：Helicobacter pylori ; Third-line eradication ; Esomeprazole ; Sitafloxacin
- 刊名：International Journal of Infectious Diseases
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：51
- 期：Complete
- 页码：66-69
- 全文大小：311 K
文摘
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A third-line Helicobacter pylori eradication regimen is not established in Japan.
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Esomeprazole is the latest proton pump inhibitor (PPI) approved in Japan, and has superior acid suppression.
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The effect of third-line therapy with esomeprazole and sitafloxacin was examined.
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Esomeprazole and sitafloxacin-based third-line therapy showed an eradication rate of 83%.
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Adverse events were comparable to those of former PPI-based therapies.