Prenylated flavonoids from Desmodium caudatum and evaluation of their anti-MRSA activity

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• 作者：Hisako Sasaki ; Yoshiki Kashiwada ; Hirofumi Shibata ; Yoshihisa Takaishi
• 关键词：Desmodium caudatum ; Fabaceae ; Prenylated flavonoid ; Anti-methicillin-resistant Staphylococcus aureus (MRSA)
• 刊名：Phytochemistry
• 出版年：2012
• 出版时间：October, 2012
• 年：2012
• 卷：82
• 期：Complete
• 页码：136-142
• 全文大小：430 K

文摘

Seven prenylated flavonoids and a prenylated chromanochroman derivative, together with eight known flavonoids, were isolated from roots of Desmodium caudatum. The 15 structures were elucidated by extensive spectroscopic analyses. The antibacterial activity of many of other compounds was evaluated against methicillin-resistant Staphylococcus aureus (MRSA: COL and 5) by a disc diffusion method, and the minimum inhibitory concentrations (MICs) to MRSA were determined.