AP1S3 is required for hepatitis C virus infection by stabilizing E2 protein
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- 作者：Xiang Li ; Yuqiang Niu ; Min Cheng ; Xiaojing Chi ; Xiuying Liu ; Wei Yang ; wyang@ipb.pumc.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：AP1S3 ; HCV ; E2 glycoprotein ; Protein degradation
- 刊名：Antiviral Research
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：131
- 期：Complete
- 页码：26-34
- 全文大小：2329 K
文摘
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Silencing AP1S3 inhibit HCV production in Huh7.5.1 cells.
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AP1S3 interacted with HCV E2 protein.
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E6AP associated with HCV E2 protein degradation.
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Synthetic peptide containing AP1S3-recognized motif suppressed HCV propagation.