Microfold Cells Actively Translocate Mycobacterium tuberculosis to Initiate Infection
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- 作者：Vidhya R. Nair1 ; 2 ; Luis H. Franco3 ; Vineetha M. Zacharia1 ; 2 ; Haaris S. Khan1 ; 2 ; Chelsea E. Stamm1 ; 2 ; Wu You1 ; 2 ; Denise K. Marciano1 ; Hideo Yagita4 ; Beth Levine3 ; 5 ; Michael U. Shiloh1 ; 2 ; michael.shiloh@utsouthwestern.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：2 August 2016
- 年：2016
- 卷：16
- 期：5
- 页码：1253-1258
- 全文大小：2387 K
文摘
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Mtb translocates across model M cells in vitro in an active, transcellular process
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Depletion of airway M cells in mice reduces Mtb dissemination via NALT
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M cells contribute to Mtb dissemination from the airway mucosa
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Airway M cell depletion in mice prior to aerosol Mtb infection improves survival