Reduced fluconazole susceptibility of Candida albicans

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• 作者：Zainab Shahid ; Jack D. Sobel
• 关键词：Candida albicans ; Vagina ; Fluconazole ; Susceptibility
• 刊名：Diagnostic Microbiology and Infectious Disease
• 出版年：2009
• 出版时间：July 2009
• 年：2009
• 卷：64
• 期：3
• 页码：354-356
• 全文大小：120 K

文摘

Fluconazole resistance and resultant failure to control Candida vaginitis (vulvovaginal candidiasis) remains extremely uncommon; however, long-term clinically relevant decrease in fluconazole susceptibility undoubtedly occurs and accompanies prolonged fluconazole chemoprophylaxis. Accordingly, in patients with refractory vaginitis or breakthrough infections due to Candida albicans, in vitro susceptibility testing is essential to optimally manage vaginitis.