The average diameters of liposomes (LBPL, BL) and liposome-formulated vaccines (LBPL-PCV2, BL-PCV2) were less than 200 nm and stable.
LBPL could significantly promote splenocyte proliferation and the cytokine secretion of macrophages in vitro.
LBPL as a vaccine adjuvant has good improvement effect on immune responses against PCV2 in vivo.