Endophilin-A2-mediated increase in scavenger receptor expression contributes to macrophage-derived foam cell formation
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- 作者：Er-Wen Huanga ; b ; 1 ; Can-Zhao Liua ; 1 ; Si-Jia Lianga ; 1 ; Zheng Zhangc ; 1 ; Xiao-Fei Lva ; Jie Liua ; Jia-Guo Zhoua ; Yong-Bo Tanga ; tangyb@mail.sysu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yong-Yuan Guana ; guanyy@mail.sysu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Foam cell formation ; Scavenger receptor ; Endophilin-A2 ; ASK1
- 刊名：Atherosclerosis
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：254
- 期：Complete
- 页码：133-141
- 全文大小：2611 K
文摘
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We identified endophilin-A2 as a novel macrophage-derived foam cell formation (MFCF)-regulating molecule.
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Endophilin-A2 regulates MFCF by regulating expression of CD36 and SR-A.
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Endophilin-A2 regulates MFCF by mechanisms attributable to and beyond endocytosis.