CTRP9 alleviated ROS production, induced the expression of PGC-1α and SIRT1 in a dose-dependent manner.
CTRP9 induced the mitochondrial biogenesis.
CTRP9 inhibited high glucose induced oxidative stress.
CTRP9 induced the mitochondrial biogenesis through upregulation of PGC-1α and SIRT1 expression.
CTRP9 induced the mitochondrial biogenesis and protected oxidative damage via the activation of AdipoR1.