Chamobtusin A, a Novel Skeleton Diterpenoid Alkaloid from Chamaecyparis obtusa cv. tetragon

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• 作者：Yu-Mei Zhang ; Ning-Hua Tan ; Yang Lu ; Ying Chang ; Rui-Rui Jia
• 刊名：Organic Letters
• 出版年：2007
• 出版时间：October 25, 2007
• 年：2007
• 卷：9
• 期：22
• 页码：4579 - 4581
• 全文大小：75K
• 年卷期：v.9,no.22(October 25, 2007)
• ISSN：1523-7052

文摘

2087hn00001>The novel diterpenoid alkaloid chamobtusin A (1) was isolated from the branches and leaves of Chamaecyparis obtusa cv. tetragon. Itsstructure and relative stereochemistry were mainly determined by MS, 2D NMR, and X-ray methods. The methanol extracts, total alkaloids ofC. obtusa cv. tetragon, and chamobtusin A were tested for their cytotoxicities against A549 and K562 human tumor cell lines.