Carryover of Maduramicin from Feed Containing Cross-Contamination Levels into Eggs of Laying Hens
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- 作者：Dorina Bodi ; Hildburg Fry ; Helmut Schafft ; Monika Lahrssen-Wiederholt ; Angelika Preiss-Weigert
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2012
- 出版时间：July 18, 2012
- 年：2012
- 卷：60
- 期：28
- 页码：6946-6952
- 全文大小：303K
- 年卷期：v.60,no.28(July 18, 2012)
- ISSN：1520-5118
文摘
Maduramicin is a coccidiostat authorized as feed additive in the European Union for chickens and turkeys for fattening but not for laying hens, considering the risk of residues in eggs. The unavoidable cross-contamination of non-target feed with coccidiostats is regulated by Commission Directive 2009/8/EC and resulting carry-over in food by Commission Regulation (EC) No. 124/2009. To verify the compliance of the maximum levels for maduramicin in feed (50 渭g/kg) and eggs (2 渭g/kg), the carry-over from feed into eggs was investigated. Diets containing 10, 30, and 50 渭g of maduramicin/kg of feed were fed to laying hens. Feed, egg white, and yolk were analyzed by LC鈥揗S/MS. Maduramicin residues were only detected in in egg yolk. Feeding the 10 渭g/kg maduramicin diet resulted in maduramicin concentrations up to 2.5 渭g/kg in whole eggs, already exceeding the maximum level. A carry-over rate of 8% maduramicin from feed into eggs was calculated.