D=jo061781an00001> |
(NHC)-Cu (NHC =
N-heterocyclic carbene) complexes efficiently catalyze
d the methylenation of avariety of aliphatic an
d aromatic al
dehy
des an
d ketones in the presence of trimethylsilyl
diazomethane,triphenylphosphine, an
d 2-propanol. The copper catalysts are not only inexpensive compare
d to rho
diumcomplexes, but they also exhibit better functional group compatibility with aromatic al
dehy
des an
d ketones.In
dee
d very high yiel
ds were obtaine
d for the formation of styrenes containing nitro, trifluoromethyl,amino, an
d ester groups, as well as for pyri
dine-, pyrrole-, an
d in
dole-substitute
d alkenes.