Recoverable (R)- and (S)-Binap-Ag(I) Complexes for the Enantioselective 1,3-Dipolar Cycloaddition Reaction of Azomethine Ylides

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• 作者：Carmen N&aacute ; jera ; M. de Gracia Retamosa ; José ; M. Sansano
• 刊名：Organic Letters
• 出版年：2007
• 出版时间：September 27, 2007
• 年：2007
• 卷：9
• 期：20
• 页码：4025 - 4028
• 全文大小：84K
• 年卷期：v.9,no.20(September 27, 2007)
• ISSN：1523-7052

文摘

The first enantioselective 1,3-dipolar cycloaddition reaction of amino acid derived azomethine ylides and maleimides catalyzed by very stableand recyclable chiral (R)- or (S)-binap-AgClO₄ complexes is described. The reactions are performed at room temperature, in good yields, withhigh endo diastereoselectivity and enantioselectivity, the complex being recovered by simple filtration.