Multifunctional Microgel Magnetic/Optical Traps for SERS Ultradetection
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- 作者：Rafael Contreras-Ca虂ceres ; Sara Abalde-Cela ; Pablo Guardia-Giro虂s ; Antonio Ferna虂ndez-Barbero ; Jorge Pe虂rez-Juste ; Ramon A. Alvarez-Puebla ; Luis M. Liz-Marza虂n
- 刊名：Langmuir
- 出版年：2011
- 出版时间：April 19, 2011
- 年：2011
- 卷：27
- 期：8
- 页码：4520-4525
- 全文大小：901K
- 年卷期：v.27,no.8(April 19, 2011)
- ISSN：1520-5827
文摘
We report on the fabrication of a SERS substrate comprising magnetic and silver particles encapsulated within a poly(N-isopropylacrylamide) (pNIPAM) thermoresponsive microgel. This colloidal substrate has the ability to adsorb analytes from solution while it is expanded (low temperature) and reversibly generate hot spots upon collapse (high temperature or drying). Additionally, the magnetic functionality permits concentration of the composite particles into small spatial regions, which can be exploited to decrease the amount of material per analysis while improving its SERS detection limit. Proof of concept for the sequestration of uncommon molecular systems is demonstrated through the first SERS analysis of pentachlorophenol (PCP), a chlorinated ubiquitous environmental pollutant.