Copper-Catalyzed Hiyama Coupling of (Hetero)aryltriethoxysilanes with (Hetero)aryl Iodides

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• 作者：Santosh K. Gurung ; Surendra Thapa ; Adarsh S. Vangala ; Ramesh Giri
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：October 18, 2013
• 年：2013
• 卷：15
• 期：20
• 页码：5378-5381
• 全文大小：296K
• 年卷期：v.15,no.20(October 18, 2013)
• ISSN：1523-7052

文摘

A Cu^I-catalyzed Hiyama coupling was achieved, which proceeds in the absence of an ancillary ligand for aryl鈥揾eteroaryl and heteroaryl鈥揾eteroaryl couplings. A P,N-ligand is required to obtain the best product yields for aryl鈥揳ryl couplings. In addition to facilitating transmetalation, CsF is also found to function as a stabilizer of the [CuAr] species, potentially generated as an intermediate after transmetalation of aryltriethoxysilanes with Cu^I-catalysts in the absence of ancillary ligands.