Study of Miscible and Immiscible Flows in a Microchannel Using Magnetic Resonance Imaging
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- 作者：Belinda S. Akpa ; Siné ; ad M. Matthews ; Andrew J. Sederman ; Kamran Yunus ; Adrian C. Fisher ; Michael L. Johns ; Lynn F. Gladden
- 刊名：Analytical Chemistry
- 出版年：2007
- 出版时间：August 15, 2007
- 年：2007
- 卷：79
- 期：16
- 页码：6128 - 6134
- 全文大小：308K
- 年卷期：v.79,no.16(August 15, 2007)
- ISSN：1520-6882
文摘
Magnetic resonance imaging (MRI) is a noninvasivetechnique that can be used to visualize mixing processesin optically opaque systems in up to three dimensions.Here, MRI has been used for the first time to obtain bothcross-sectional velocity and concentration maps of flowthrough an optically opaque Y-shaped microfluidic sensor.Images of 23 
m × 23 m resolution were obtained for achannel of rectangular cross section (250 m × 500 m)fed by two square inlets (250 m × 250 m). Bothmiscible and immiscible liquid systems have been studied. These include a system in which the coupling of flowand mass transfer has been observed, as the diffusion ofthe analyte perturbs local hydrodynamics. MRI has beenshown to be a versatile tool for the study of mixingprocesses in a microfluidic system via the multidimensional spatial resolution of flow and mass transfer.
m × 23 m resolution were obtained for achannel of rectangular cross section (250 m × 500 m)fed by two square inlets (250 m × 250 m). Bothmiscible and immiscible liquid systems have been studied. These include a system in which the coupling of flowand mass transfer has been observed, as the diffusion ofthe analyte perturbs local hydrodynamics. MRI has beenshown to be a versatile tool for the study of mixingprocesses in a microfluidic system via the multidimensional spatial resolution of flow and mass transfer.