A Three-Station DNA Catenane Rotary Motor with Controlled Directionality

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• 作者：Chun-Hua Lu ; Alessandro Cecconello ; Johann Elbaz ; Alberto Credi ; Itamar Willner
• 刊名：Nano Letters
• 出版年：2013
• 出版时间：May 8, 2013
• 年：2013
• 卷：13
• 期：5
• 页码：2303-2308
• 全文大小：328K
• 年卷期：v.13,no.5(May 8, 2013)
• ISSN：1530-6992

文摘

The assembly of DNA machines represents a central effort in DNA nanotechnology. We report on the first DNA rotor system composed of a two-ring catenane. The DNA rotor ring rotates in dictated directions along a wheel, and it occupies three distinct sites. Hg²⁺/cysteine or pH (H⁺/OH鈥?/sup>) act as fuels or antifuels in positioning the rotor ring. Analysis of the kinetics reveals directional clockwise or anticlockwise population of the target-sites (>85%), and the rotor鈥檚 direction is controlled by the shortest path on the wheel.

Keywords:

DNA; machine; catenane; nanotechnology; fluorescence resonance energy transfer (FRET)