Epoxidation of Olefins with a Silica-Supported Peracid in Supercritical Carbon Dioxide under Flow Conditions
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- 作者：Rossella Mello ; Ana Alcalde-Aragon茅s ; Andrea Olmos ; Mar铆a Elena Gonz谩lez-N煤帽ez ; Gregorio Asensio
- 刊名：The Journal of Organic Chemistry
- 出版年：2012
- 出版时间：May 18, 2012
- 年：2012
- 卷：77
- 期：10
- 页码：4706-4710
- 全文大小：275K
- 年卷期：v.77,no.10(May 18, 2012)
- ISSN：1520-6904
文摘
Anhydrous 2-percarboxyethyl-functionalized silica (2b), a recyclable supported peracid, is a suitable reagent to perform the epoxidation of alkenes 1 in supercritical carbon dioxide at 250 bar and 40 掳C under flow conditions. This procedure simplifies the isolation of the reaction products and uses only carbon dioxide as a solvent under mild conditions. The solid reagent 2b can be easily recycled by a reaction with 30% hydrogen peroxide in an acid medium.