Assigning the Algal Source of Dimethylsulfide Using a Selective Lyase Inhibitor

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• 作者：Uria Alcolombri ; Lei Lei ; Diana Meltzer ; Assaf Vardi ; Dan S. Tawfik
• 刊名：ACS Chemical Biology
• 出版年：2017
• 出版时间：January 20, 2017
• 年：2017
• 卷：12
• 期：1
• 页码：41-46
• 全文大小：336K
• ISSN：1554-8937

文摘

Atmospheric dimethylsulfide (DMS) is massively produced in the oceans by bacteria, algae, and corals. To enable identification of DMS sources, we developed a potent mechanism-based inhibitor of the algal Alma dimethylsulfoniopropionate lyase family that does not inhibit known bacterial lyases. Its application to coral holobiont indicates that DMS originates from Alma lyase(s). This biochemical profiling may complement meta-genomics and transcriptomics to provide better understanding of the marine sulfur cycle.