Mixed f−d Coordination Complexes as Dual Visible- and Near-Infrared-Emitting Probes for Targeting DNA

详细信息    查看全文

• 作者：Aline M. Nonat ; Susan J. Quinn ; Thorfinnur Gunnlaugsson
• 刊名：Inorganic Chemistry
• 出版年：2009
• 出版时间：June 1, 2009
• 年：2009
• 卷：48
• 期：11
• 页码：4646-4648
• 全文大小：787K
• 年卷期：v.48,no.11(June 1, 2009)
• ISSN：1520-510X

文摘

A new family of mixed-lanthanide (Yb^III and Nd^III) transition-metal (f−d) cyclen-Ru^II(phen)₃ (phen = 1,10-phenanthroline) complexes were synthesized as dual visible- and near-infrared (NIR)-emitting DNA probes/sensors. Significant changes were seen in both the Ru^II visible and the Yb^III-centered NIR emission, which was switched off upon binding to DNA at pH 7.4. In contrast, no changes were seen in the Nd^III emission of the analogue f−d conjugate.