Iridium(I) Complexes of Upper Rim Functionalized PTA Derivatives. Synthesis, Characterization, and Use in Catalytic Hydrogenations (PTA = 1,3,5-Triaaza-7-phosphaadamantane)

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• 作者：Antonella Guerriero ; Mikael Erlandsson ; Andrea Ienco ; Donald A. Krogstad ; Maurizio Peruzzini ; Gianna Reginato ; Luca Gonsalvi
• 刊名：Organometallics
• 出版年：2011
• 出版时间：April 11, 2011
• 年：2011
• 卷：30
• 期：7
• 页码：1874-1884
• 全文大小：1032K
• 年卷期：v.30,no.7(April 11, 2011)
• ISSN：1520-6041

文摘

Reaction of (1,3,5-triaza-7-phosphaadamantane-6-yl)lithium (1; PTA-Li), synthesized in high yield and purity, with p-(dimethylamino)benzaldehyde gave the novel water-soluble 尾-phosphino alcohol (4鈥?(dimethylamino)phenyl)(1,3,5-triaza-7-phosphatricyclo[3.3.1.1]dec-6-yl)methanol (2; PZA-NMe₂). The oxide O鈺怭ZA-NMe₂ (3) and sulfide S鈺怭ZA-NMe₂ (4) were also obtained. Ir(I) complexes of (SR,RS)-PZA-NMe₂ and the analogue phenyl(1,3,5-triaza-7-phosphatricyclo[3.3.1.1]dec-6-yl)methanol (PZA) were obtained and used as precatalysts for the hydrogenation of 伪,尾-unsaturated aldehydes and ketones and acetophenone using different mild reduction protocols. The X-ray crystal structure of the SR,RS diastereoisomer of PZA-NMe₂ was also obtained and is described herein.