Covalent Attachment of Polymersomes to Surfaces

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• 作者：Stephanie Domes ; Volkan Filiz ; Jasmin Nitsche ; Andreas Frmsdorf ; Stephan Frster
• 刊名：Langmuir
• 出版年：2010
• 出版时间：May 18, 2010
• 年：2010
• 卷：26
• 期：10
• 页码：6927-6931
• 全文大小：842K
• 年卷期：v.26,no.10(May 18, 2010)
• ISSN：1520-5827

文摘

We show that vesicles made of block copolymers with aldehyde end groups can be covalently attached to aminated and non-aminated, untreated glass surfaces. The attached vesicles were sufficiently stable to allow a detailed investigation of vesicle shapes by confocal laser scanning microscopy (CLSM) and AFM in aqueous solutions allowing reconstruction of 3D images of the vesicle structure. Covalently attached PCL−PEO, PLA−PEO, and PI−PEO block copolymer vesicles have different footprint areas and different shapes due to their differences in bilayer stiffness.