Efficient Chromium(II)-Catalyzed Cross-Coupling Reactions between Csp2 Centers

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• 作者：Andreas K. Steib ; Olesya M. Kuzmina ; Sarah Fernandez ; Dietmar Flubacher ; Paul Knochel
• 刊名：Journal of the American Chemical Society
• 出版年：2013
• 出版时间：October 16, 2013
• 年：2013
• 卷：135
• 期：41
• 页码：15346-15349
• 全文大小：302K
• 年卷期：v.135,no.41(October 16, 2013)
• ISSN：1520-5126

文摘

Low-toxicity chromium(II) chloride catalyzes at 25 掳C within minutes the coupling reactions of various (hetero)arylmagnesium reagents with N-heterocyclic halides, aromatic halogenated ketones or imines, and alkenyl iodides. Remarkably, much lower amounts of homo-coupling side products are obtained compared to related iron, cobalt, or manganese cross-couplings.