Tetraalkylphosphonium-Based Ionic Liquids for a Single-Step Dye Extraction/MALDI MS Analysis Platform

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• 作者：Katherine S. Lovejoy ; Geraldine M. Purdy ; Srinivas Iyer ; Timothy C. Sanchez ; Al Robertson ; Andrew T. Koppisch ; Rico E. Del Sesto
• 刊名：Analytical Chemistry
• 出版年：2011
• 出版时间：April 15, 2011
• 年：2011
• 卷：83
• 期：8
• 页码：2921-2930
• 全文大小：913K
• 年卷期：v.83,no.8(April 15, 2011)
• ISSN：1520-6882

文摘

Room temperature ionic liquids, or RTILs, based on tetraalkylphosphonium (PR₄⁺) cations were used as the basis of a platform that enables separation of dyes from textiles, extraction of dyes from aqueous solution, and identification of the dyes by MALDI-MS in a single experimental step for forensic purposes. Ionic liquids were formed with PR₄⁺ cations and ferulate (FA), 伪-cyano-4-hydroxycinnamate (CHCA), and 2,5-dihydroxybenzoate (DHB) anions. The use of tetraalkylphosphonium-based ionic liquids in MALDI-MS allowed detection of small molecule dyes without addition of a traditional solid MALDI matrix.