WFIGR ID=jo0625655n00002>![](/isubscribe/journals/joceah/72/i07/figures/jo0625655n00002.gif) |
Enantioselective copper-catalyzed allylic alkylations
were performed on allylic bromides
with a protectedhydroxyl or amine functional group using several Grignard reagents and Taniaphos
L1 as a ligand. Theterminal olefin moiety in the products
was transformed into various functional groups
without racemization,providing facile access to a variety of versatile bifunctional chiral building blocks.