Bioactive Star Gels

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• 作者：M. Manzano ; D. Arcos ; M. Rodrí ; guez Delgado ; E. Ruiz ; F. J. Gil ; M. Vallet-Regí
• 刊名：Chemistry of Materials
• 出版年：2006
• 出版时间：November 28, 2006
• 年：2006
• 卷：18
• 期：24
• 页码：5696 - 5703
• 全文大小：722K
• 年卷期：v.18,no.24(November 28, 2006)
• ISSN：1520-5002

文摘

Star gels hybrid materials, suitable for use in bone repair, have been synthesized by the sol-gel method,incorporating a calcium alkoxide to the synthesis process. To determine the network connectivity andthe Ca²⁺ cation location into the hybrid network, the physical and chemical properties of star gels withdifferent compositions have been studied. In vitro bioactivity tests evidence that the star gels develop anapatite-like phase on their surface in contact with simulated body fluid, although this property dependson the Si/Ca ratio. Finally, the study of mechanical properties demonstrated that star gels are less rigidthan conventional bioactive glasses, show similar fracture toughness values than cortical bone, and pointto excellent long-term fatigue behavior.