Eleganketal A, a Highly Oxygenated Dibenzospiroketal from the Marine-Derived Fungus Spicaria elegans KLA03
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- 作者：Yepeng Luan ; Hongjuan Wei ; Zhenpei Zhang ; Qian Che ; Yankai Liu ; Tianjiao Zhu ; Attila M谩ndi ; Tibor Kurt谩n ; Qianqun Gu ; Dehai Li
- 刊名：Journal of Natural Products
- 出版年：2014
- 出版时间：July 25, 2014
- 年：2014
- 卷：77
- 期：7
- 页码：1718-1723
- 全文大小：314K
- ISSN：1520-6025
文摘
Eleganketal A (1), a naturally occurring aromatic polyketide possessing a rare highly oxygenated spiro[isobenzofuran-1,3鈥?isochroman] ring system, was isolated from the fungus Spicaria elegans KLA03 by culturing it in a modified mannitol-based medium. The structure of 1 including the absolute configuration was determined by combining spectroscopic analysis, synthesis of the racemic permethylated analogue, chiral-phase HPLC separation, and TDDFT-ECD analysis.