Biomimetic Synthesis of Polycyclic Polyprenylated Acylphloroglucinol Natural Products Isolated from Hypericum papuanum

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• 作者：Jonathan H. George ; Micha D. Hesse ; Jack E. Baldwin ; Robert M. Adlington
• 刊名：Organic Letters
• 出版年：2010
• 出版时间：August 6, 2010
• 年：2010
• 卷：12
• 期：15
• 页码：3532-3535
• 全文大小：217K
• 年卷期：v.12,no.15(August 6, 2010)
• ISSN：1523-7052

文摘

Biomimetic syntheses of three polycylic polyprenylated acylphloroglucinol natural products isolated from Hypericum papuanum, ialibinone A, ialibinone B, and hyperguinone B, have been accomplished by selective oxidative cyclizations of the proposed biosynthetic precursor 5, which was synthesized from phloroglucinol in three steps.