Synthesis, Crystal Structures, Photophysical Properties, and Bioimaging of Living Cells of Bis-尾-Diketonate Phenothiazine Ligands and Its Cyclic Dinuclear Complexes

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• 作者：Dongmei Li ; Xiaohe Tian ; Guiju Hu ; Qiong Zhang ; Peng Wang ; Pingping Sun ; Hongping Zhou ; Xiangming Meng ; Jiaxiang Yang ; Jieying Wu ; Baokang Jin ; Shengyi Zhang ; Xutang Tao ; Yupeng Tian
• 刊名：Inorganic Chemistry
• 出版年：2011
• 出版时间：September 5, 2011
• 年：2011
• 卷：50
• 期：17
• 页码：7997-8006
• 全文大小：1239K
• 年卷期：v.50,no.17(September 5, 2011)
• ISSN：1520-510X

文摘

Two bis-尾-diketones, RCOCH₂CO-EPTZ-COCH₂COR (EPTZ = 10-ethylphenothiazine; R = C₆H₅ for H₂L¹ and CF₃ for H₂L²) and their cyclic dinuclear Zn(II), Cd(II), Ni(II), Mn(II), Cu(II), Co(II) complexes have been synthesized and fully characterized. Their crystal structures were determined by single crystal X-ray diffraction analysis. Their photophysical properties have been further investigated both experimentally and theoretically. The results revealed that significant enhancement of two-photon absorption cross section values were obtained for the cyclic dinuclear Zn(II) and Cd(II) complexes compared with their free ligands. Additionally, confocal microscopy and two-photon microscopy fluorescent imaging of MCF-7 cells labeled with two ligands and Zn(II) complexes reveal their potential applications as a biological fluorescent probe.