Struggle for Quality in Determination of Perfluorinated Contaminants in Environmental and Human Samples
详细信息 查看全文
- 作者：Stefan P. J. van Leeuwen ; Anna Kä ; rrman ; Bert van Bavel ; Jacob de Boer ; Gunilla Lindströ ; m
- 刊名：Environmental Science & Technology
- 出版年：2006
- 出版时间：December 15, 2006
- 年：2006
- 卷：40
- 期：24
- 页码：7854 - 7860
- 全文大小：217K
- 年卷期：v.40,no.24(December 15, 2006)
- ISSN：1520-5851
文摘
The first worldwide interlaboratory study on the analysesof 13 perfluorinated compounds (PFCs) in three environmental and two human samples indicates a varying degreeof accuracy in relation to the matrix or analyte determined.The ability of 38 participating laboratories from 13countries to determine the analytes in the various matriceswas evaluated by calculation of z-scores according tothe Cofino model. The PFCs which were reported mostfrequently by the laboratories, and assessed with the mostsatisfactory agreement, were perfluorooctane sulfonate(PFOS) and perfluorooctanoic acid (PFOA). In general, thelevel of agreement between the participating laboratoriesdecreased in the following order: PFC standard solution(76% satisfactory z-scores of <
2 for PFOS) < humanblood (67%) < human plasma (63%) < fish liver extract (55%)< water (31%) < fish tissue (17%). This shows thatrelative good agreement between laboratories was obtainedfor the study of standard and human matrices. For thefish extract, most laboratories underestimated the actualPFOS concentration due to matrix effects. The results for thefish tissue and water are also poor, indicating that theextraction and cleanup steps require further improvement.It was concluded that the PFC determinations in variousmatrices are not yet fully mastered.
2 for PFOS) < humanblood (67%) < human plasma (63%) < fish liver extract (55%)< water (31%) < fish tissue (17%). This shows thatrelative good agreement between laboratories was obtainedfor the study of standard and human matrices. For thefish extract, most laboratories underestimated the actualPFOS concentration due to matrix effects. The results for thefish tissue and water are also poor, indicating that theextraction and cleanup steps require further improvement.It was concluded that the PFC determinations in variousmatrices are not yet fully mastered.