Hydrazone as the Directing Group for Ir-Catalyzed Arene Diborylations and Sequential Functionalizations
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- 作者：Abel Ros ; Roc铆o L贸pez-Rodr铆guez ; Beatriz Estepa ; Eleuterio 脕lvarez ; Rosario Fern谩ndez ; Jos茅 M. Lassaletta
- 刊名：The Journal of the American Chemical Society
- 出版年：2012
- 出版时间：March 14, 2012
- 年：2012
- 卷：134
- 期：10
- 页码：4573-4576
- 全文大小：324K
- 年卷期：v.134,no.10(March 14, 2012)
- ISSN：1520-5126
文摘
The use of hemilabile pyridine鈥揾ydrazone N,N-ligands allows the highly selective Ir-catalyzed ortho,ortho鈥?directed diborylation of aromatic N,N-dimethylhydrazones in near-quantitative yields. One-pot sequential Suzuki鈥揗iyaura cross-coupling with different aryl bromides provides a short entry to unsymmetrically substituted 2,6-diarylbenzaldehyde derivatives.