A G-Quadruplex Ligand with 10000-Fold Selectivity over Duplex DNA
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- 作者：Isabelle M. Dixon ; Fré ; dé ; ric Lopez ; Agueda M. Tejera ; Jean-Pierre Estè ; ve ; Maria A. Blasco ; Geneviè ; ve Pratviel ; Bernard Meunier
- 刊名：Journal of the American Chemical Society
- 出版年：2007
- 出版时间：February 14, 2007
- 年：2007
- 卷：129
- 期：6
- 页码：1502 - 1503
- 全文大小：41K
- 年卷期：v.129,no.6(February 14, 2007)
- ISSN：1520-5126
文摘
A cationic manganese porphyrin binds strongly and selectively to G-quadruplex DNA. This compound is the most selective G4-ligand reported to date.