Online-Calibration for Reliable and Robust Lab-on-a-Chip Surface Enhanced Raman Spectroscopy Measurement in a Liquid/Liquid Segmented Flow

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• 作者：Anne M盲rz ; Thomas Bocklitz ; J眉rgen Popp
• 刊名：Analytical Chemistry
• 出版年：2011
• 出版时间：November 1, 2011
• 年：2011
• 卷：83
• 期：21
• 页码：8337-8340
• 全文大小：713K
• 年卷期：v.83,no.21(November 1, 2011)
• ISSN：1520-6882

文摘

Concerning the usability of lab-on-a-chip surface enhanced Raman spectroscopy (LOC-SERS) for analytical tasks applying chemometric data evalutation, a secure, reproducible, and stable data output independent of inconsistent ambient conditions has to be accomplished. In this contribution, we present a new approach to achieve reliable and robust measurements based on segmented flow LOC-SERS via online-wavenumber calibration.