Novel BODIPY-Based Fluorescence Turn-on Sensor for Fe3+ and Its Bioimaging Application in Living Cells

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• 作者：Binglin Sui ; Simon Tang ; Taihong Liu ; Bosung Kim ; Kevin D. Belfield
• 刊名：ACS Applied Materials & Interfaces
• 出版年：2014
• 出版时间：November 12, 2014
• 年：2014
• 卷：6
• 期：21
• 页码：18408-18412
• 全文大小：299K
• ISSN：1944-8252

文摘

A novel boron-dipyrromethene (BODIPY) based fluorescence turn-on sensor for detecting Fe³⁺ in aqueous media is reported with 23-fold fluorescence enhancement. The sensor is comprised of a combination of BODIPY fluorophore and a new Fe³⁺-recognizing cryptand that exhibits high selectivity, sensitivity, and reversibility toward Fe³⁺ detection. Cell imaging studies demonstrate that this sensor is capable of sensing Fe³⁺ in living cells.

Keywords:

iron(III); fluorescent sensor; BODIPY; cryptand; cell imaging; metal ion sensor