The Alga Ochromonas danica Produces Bromosulfolipids

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• 作者：Alexander R. White ; Brendan M. Duggan ; Shiou-Chuan Tsai ; Christopher D. Vanderwal
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：March 4, 2016
• 年：2016
• 卷：18
• 期：5
• 页码：1124-1127
• 全文大小：271K
• ISSN：1523-7052

文摘

Many halogenases interchangeably incorporate chlorine and bromine into organic molecules. On the basis of an unsubstantiated report that the alga Ochromonas danica, a prodigious producer of chlorosulfolipids, was able to produce bromosulfolipids, we have investigated the promiscuity of its halogenases toward bromine incorporation. We have found that bromosulfolipids are produced with the exact positional and stereochemical selectivity as in the chlorosulfolipid danicalipin A when this alga is grown under modified conditions containing excess bromide ion.