Bioavailability, Toxicity, and Bioaccumulation of Quantum Dot Nanoparticles to the Amphipod Leptocheirus plumulosus

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• 作者：Brian P. Jackson ; Deenie Bugge ; James F. Ranville ; Celia Y. Chen
• 刊名：Environmental Science & Technology (ES&T)
• 出版年：2012
• 出版时间：May 15, 2012
• 年：2012
• 卷：46
• 期：10
• 页码：5550-5556
• 全文大小：294K
• 年卷期：v.46,no.10(May 15, 2012)
• ISSN：1520-5851

文摘

Understanding the relative toxicities of different modes of nanoparticle exposure as compared with their dissolved metal ions are emerging areas in ecotoxicology. Here, we report on bioavailability, toxicity, and bioaccumulation of carboxyl-functionalized CdSe/ZnS quantum dots (QDs) to the amphipod Leptocheirus plumulosus exposed to equivalent Cd concentrations via dissolved Cd, QDs in water, or QDs in algal food. Both modes of QD exposure were accumulated to greater extent than dissolved Cd. Exposure to QDs via algae resulted in high amphipod mortality. Cadmium and Se in amphipods exposed to QDs in water were highly correlated and spatially localized within the amphipod. In contrast, when exposed to QDs via algae the metals were more disperse and not highly correlated suggesting QD dissolution and resultant metal ion toxicity. This study suggests QDs are accumulated to a greater extent than the dissolved ion and could lead to trophic transfer. QDs ingested with algae are bioavailable and result in toxicity, which is not observed in the absence of algae.