Photo-Induced Pyridine Substitution in cis-[Ru(bpy)2(py)2]Cl2: A Snapshot by Time-Resolved X-ray Solution Scattering

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• 作者：Luca Salassa ; Elisa Borfecchia ; Tiziana Ruiu ; Claudio Garino ; Diego Gianolio ; Roberto Gobetto ; Peter J. Sadler ; Marco Cammarata ; Michael Wulff ; Carlo Lamberti
• 刊名：Inorganic Chemistry
• 出版年：2010
• 出版时间：December 6, 2010
• 年：2010
• 卷：49
• 期：23
• 页码：11240-11248
• 全文大小：1004K
• 年卷期：v.49,no.23(December 6, 2010)
• ISSN：1520-510X

文摘

Determination of transient structures in light-induced processes is a challenging goal for time-resolved techniques. Such techniques are becoming successful in detecting ultrafast structural changes in molecules and do not require the presence of probe-like groups. Here, we demonstrate that TR-WAXS (Time-Resolved Wide Angle X-ray Scattering) can be successfully employed to study the photochemistry of cis-[Ru(bpy)b>2b>(py)b>2b>]Clb>2b>, a mononuclear ruthenium complex of interest in the field of photoactivatable anticancer agents. TR-WAXS is able to detect the release of a pyridine ligand and the coordination of a solvent molecule on a faster timescale than 800 ns of laser excitation. The direct measurement of the photodissociation of pyridine is a major advance in the field of time-resolved techniques allowing detection, for the first time, of the release of a multiatomic ligand formed by low Z atoms. These data demonstrate that TR-WAXS is a powerful technique for studying rapid ligand substitution processes involving photoactive metal complexes of biological interest.