详细信息    查看全文

• 作者：Jos&eacute ; M. Concelló ; n ; Humberto Rodrí ; guez-Solla ; Carmen M&eacute ; jica ; Elena G. Blanco ; Santiago Garcí ; a-Granda ; M. Rosario Dí ; az
• 刊名：Organic Letters
• 出版年：2008
• 出版时间：January 17, 2008
• 年：2008
• 卷：10
• 期：2
• 页码：349 - 352
• 全文大小：63K
• 年卷期：v.10,no.2(January 17, 2008)
• ISSN：1523-7052

文摘

A novel chromium-promoted alkyl- and silyl cyclopropanation of (E)- or (Z)-,-unsaturated amides in which the C-C double bond is di-, ortrisubstituted is described. This process takes place with total stereospecificity, and the new stereogenic center is generated with high or totalstereoselectivity. A mechanism is proposed to explain the cyclopropanation reaction.