Functional Cationic Nanomagnet−Porphyrin Hybrids for the Photoinactivation of Microorganisms
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- 作者：Carla M. B. Carvalho ; Eliana Alves ; Liliana Costa ; João P. C. Tomé ; Maria A. F. Faustino ; Maria G. P. M. S. Neves ; Augusto C. Tomé ; José A. S. Cavaleiro ; Adelaide Almeida ; Ângela Cunha ; Zhi Lin ; João Rocha
- 刊名：ACS Nano
- 出版年：2010
- 出版时间：December 28, 2010
- 年：2010
- 卷：4
- 期：12
- 页码：7133-7140
- 全文大小：352K
- 年卷期：0
- ISSN：1936-086X
文摘
Cationic nanomagnet−porphyrin hybrids were synthesized and their photodynamic therapy capabilities were investigated against the Gram (−) Escherichia coli bacteria, the Gram (+) Enterococcus faecalis bacteria and T4-like phage. The synthesis, structural characterization, photophysical properties, and antimicrobial activity of these new materials are discussed. The results show that these new multicharged nanomagnet−porphyrin hybrids are very stable in water and highly effective in the photoinactivation of bacteria and phages. Their remarkable antimicrobial activity, associated with their easy recovery, just by applying a magnetic field, makes these materials novel photosensitizers for water or wastewater disinfection.