High-Fidelity Stereochemical Memory in a FeII4L4 Tetrahedral Capsule

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• 作者：Ana M. Castilla ; Naoki Ousaka ; Rana A. Bilbeisi ; Elisa Valeri ; Tanya K. Ronson ; Jonathan R. Nitschke
• 刊名：Journal of the American Chemical Society
• 出版年：2013
• 出版时间：November 27, 2013
• 年：2013
• 卷：135
• 期：47
• 页码：17999-18006
• 全文大小：455K
• 年卷期：v.135,no.47(November 27, 2013)
• ISSN：1520-5126

文摘

A new class of Fe^II₄L₄ capsules, based upon a tritopic trialdehyde subcomponent, is reported. One such capsule was prepared diastereoselectively through the incorporation of a chiral amine residue. This amine was displaced by an achiral one, while maintaining the stereochemistry of the cage framework (99% ee); this cage retained its stereochemistry even after 4 days at 90 掳C. Mechanistic studies indicate the memory displayed by this capsule to be the result of effective stereochemical communication between the metal centers mediated by the rigid 3-fold-symmetric faces, in combination with a stepwise substitution mechanism.